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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e5432387edd7af071d8ec3e6df837f3ae1fbaf14a8f448fc2554452abea41763' 
  AND token = 'TEIFfFm15qKPiJc1iPJLxBHQzrGa4ULl8dDbCUmoclI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}