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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'be48257ca387aba67a329a55aab6756927fb7f4868b8e3c998b7c64e80275dfe' 
  AND token = '+U7gRJGDy49gQKd6mnoGu2LKc15KyI2UCGJzpR02NlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}