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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4acf31fd3dc4b7a6ec257dc72aeef2b3910f091fddd79052d5abba14a0448301' 
  AND token = 'fX+et1z24sDuTfVYeyWp0MV5IjYYDxoIPhks59pIg1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}