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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0de3ff11ba0ac817455aebef9780e46e0ef1f35f580dba73e4a33627d2d2e03a' 
  AND token = 'ME2fx1jW4c0z8moxx20GWW8CXNPAXSWGdKy0bkVfjcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}