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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0a721a5affecec284dd412e39305bd2e874ec7de51161e97753ee753e399fa8c' 
  AND token = 'RV8FrLL7NNbdxKSKd0BXyyTztsi8IVwRGtPA5Dw0LqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}