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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '646dcdc6b2d06d4354145c8ae306ae121eba5f01e12d51b4f42a378fe372b92b' 
  AND token = '+o6XO4ASpcPwZOqiOvXfqkRh+P90vk6v1AOGC2yOVm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}