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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b64d927ba1a26f8543c658689dbac22c6dfbd7528f7065f7d803f7d96f377000' 
  AND token = '52nGMO+HzKd/XcmH6ZoUmdNMRcoIEwJd6CTrx6yXiok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}