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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd0e3271362d2eb5d420ed456c314fa6bf5a1998f8b7f79f76a5e246dcecfafb1' 
  AND token = '+SVoHrbdAetk/RyVsx/9LX2/E/yZdhZ7aGZZW8S+EQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}