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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '00db21a35323d78c0c6abb01b5430a26f8327f3fa8589ed2a594f4be3648701e' 
  AND token = 'IxvtM32eH1tzA6WZwCaD+z+hRFZNgra9C2lnlLg53Mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}