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SELECT 
  1 
FROM 
  cscart_aprilec_print_temp_designs 
WHERE 
  session_id = 'VXNV-26D5-SEOD-KIEO-ZICL-BO8V-A4C6-9V43' 
  AND product_id = 207 
  AND expires_at > 1778149909 
  AND confirmed = 'Y' 
LIMIT 
  1

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}