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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5313d81707ec96d5eb8885eb32d5eb6c9913d0b2c9c6773c047333f307978e2a' 
  AND token = '++SilvAvKuZaz74IC3ATZ1NmbAuAU5Y8Va/vLoF1ISc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}