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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1c6422957184461c6ab1ad66bda7e6ac37c3122fc45031fffa2606dbfc34da12' 
  AND token = 'Xnrwf+4gsgY0hRXO+EPC1PY4UqMPChA5Jp0uitDfZFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}