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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b43276c004ece14b0295498bfe43802815b3a3cd5bbf7a980463b1dead631515' 
  AND token = 'Zv2atO82C1SUm4AfjKbY2N+6Iwf6tSyj6xEjtfzfrow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}