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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'aa9243914d597b5df82148504dd150e00a8df4f4b3fe366596473f7a3975d806' 
  AND token = 'rFeiGMJPp0TWXtnfB57f3jy52sqVqemMoiEB0eWpuzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}