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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '88224fd1abb20e87769243fd65c8b49960cfd6348897af7a5c8231fc25a8617e' 
  AND token = '1pe2Dplwq3bMfw0wL7rm2ELjknreUUwQroGawFNCwzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}