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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '54252a88fd4588699ba979408f707478dca85070b8f98a4a97d9de88a9302253' 
  AND token = 'JxilfTfuSHc6+jQm3TYDqFkDgYtkVfFhGOOxa7sloVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}