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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3d3f01a6dd4deefdc974923f593e657b25ff02a3d2e4bd160e4bd5dbfb322402' 
  AND token = 'IT0RxzWQsGLMfNQSfeNqPg+Dr+TPoG/5CO80Tv47Iqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}