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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd81c9f2cac7231b1df127e8c832a7534490290a2dd62f03f4bd4d54b99038ab3' 
  AND token = 'DWRrxTXftw0Q/8YebdzoudmeDZE3uOGqPR4dzVTTAcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}