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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '25698c39b7a2d25141314d33f72ba6279ee83daead2e862567181cc032533770' 
  AND token = 'ugJrbyvwsXr+6RMgqunt+XU5aJJJJQUSkPcP5PRECCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}