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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '35fd5eebce770a37901653b8701eace997f0a1ca0a2c8ee1e928748a9e999dd7' 
  AND token = 'BEP2FKhp3fZ4/eUPAgFwpJWApbTZBz52DxgP+XlmDww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}