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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0387cb9061c92dbf9cdbd0c5bd5081645dc6612ea683f11958b1725be1cb1795' 
  AND token = 'CCX2SNMZH9V3gyUjnmdRFtwl+2hsLM9kc3/IPZo2cpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}