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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '67b37908680f911fab3be5dc1ba8b21f75e50ab4f0a08b4a4322cf86b6204ace' 
  AND token = 'vDLLA0Cs2+ieCN1KdUOo87eHH7kcYPE5dQuEUjWzfJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}