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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '610b4d825c82c4a42b463aaee5e6e7978084d6dece9946be0baa58bfeaa22600' 
  AND token = 'xvZaHAt57JpOtkC/ww0A+EUObs3qwH2ZlMoZtM0um6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}