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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '65146d9a25a4cd4c659c4aa96ca310867113a1629f7c87d51b6d2f936078b845' 
  AND token = 'qNdshNdWOTJ9PHoD+oulxY/eib9iSqNfoDaAAgzF6G8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}