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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '371f042426c448b3fe799b66b3a8d3f4f9be7a7c355b049bd049806305abea8f' 
  AND token = '3F7uqcEMLLBue8+HrCaI4OUiUA2ej9GgL8dBgS9tgkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}