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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '68f3c9f2572872588fb33335f71c7e1f4ea49534d63e7a16794c3595a54f1606' 
  AND token = 'vYikPINZK8TGaWMXNKw8bsmcMFai8KuyMt1fdmpy1Mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}