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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '51f5be9e013ec6184bfd096aaea8e307eb37ea7d4e5d5749d2b5d8918361111d' 
  AND token = 'z/J8U4OR8TCH/IlcxNGdHEkXfQtt9bJNUzprWHPhCUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}