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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c22d795c3b576e72787799134e3126ad0c3bfe9b857c44f325b658665b2a4bed' 
  AND token = 'wQf6j/usS4/xfbORTiKk6HlasoInFFZoB00BySBEQbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}