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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '12c16dcb94df9a3fe14773cdcd6c591acc4d9ab18ff5092b23d0327f49af3afb' 
  AND token = 'slFrVb5IrvNlpXtpa+Kf7jS6TyA0/pZgT2HwmGcHgNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}