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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8514080fcdff82b62a0fc581d99f769ba274e58b19721841705793e24b57c666' 
  AND token = 'pnPYBDUU/JS270e8rpEFLC0Vvyk/Fjo72bhj6sxEEm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}