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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '72823549364279dc0f03f9c559a63661b5c1bce6fe85a6f69ea125319f6b1fac' 
  AND token = 'vtyUxlBblpCUie+lOv50Fj75TZ3OytipDUHsSmkfaBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}