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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '368ec72c0f4a7c1ab0483f1f871430750165ae98548355f200357b86089a8847' 
  AND token = 'B+4A9noEtdiDZwIyxC5Xgq42pK7nJpc+zvcSEaXCi7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}