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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '788e877fc04b07607f4fd8b2b3cedc646b18a2e88880251b369f778f1f8a5d82' 
  AND token = 'mItBfhb3i8W17VICZdAoPh7m4NTD4bRLwgrUtQnVOig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}