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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd0ec285859e5c2001b2384d21d144d2e2d32274b0e0534f7c970dcbf14973c0b' 
  AND token = 'qv6xwQQWSBTZHQMF1NUtqSm9GtT0cQRlla6PS1vCIE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}