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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd70412a6b948ad24919d59b45e195f55cdfabbb650ab01042b394633c0386d1d' 
  AND token = '3hkbDI/GCCHc4IRTEiv3VL2rYYGtgjulH0BAvG5tvoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}