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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e3f48f17bf33e88f70625c3ccc981f08c96a2b05a5d9f9933548d4f35c225739' 
  AND token = 'wBpj2Q8uKdRR6l03Qmmh1Td82Jz6LCER2aZfKIcwQHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}