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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '99d55394c83c08a881be2958bc27c2ddb3985722111bcbc232e789b156256071' 
  AND token = 'Yj3dcO/4wkd2JtiHS0y5ApAflzYwI7lWUxanU2j9MZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}