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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4d4e9ec4bd1bdce9fd46a9101802e3de4b052524a65362b252b4f954e4e34708' 
  AND token = '5Wd6m4v6PW+j/zd0sN3GElQZTmSiZOmsvyG5Al9i8Ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}