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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1344251251bd27d902e06270d80107d2aae9e7f7c18b0a15bdb4019db932a906' 
  AND token = 'DCXx6tm2Jb8J73VU4UKN1bhW8zN6OKOs/WbgTpNb4IU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}