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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5573fb7259cc8e57af1b94e84eff5be69b4bcfed705ced68276c31f66f6109eb' 
  AND token = '7pEj6PY6x4QV8yXESAhrYAVWdePdTuK4c1MIalfDgDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}