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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5cced6e35eac49626e55f276acf8b522590490c91932681a5e559078d2afa34f' 
  AND token = 'Ho6PMvYU+LZD+DPfT0DaFFs7FXWgaNa5xNzHAl+3gRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}