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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2ba91c9b7aa22276f6a5cf9022d8388cf80acca23dcc735d2257b206202c03b0' 
  AND token = 'V8QeS2iqu5PFfv0ZnTb+W4D1LxIi+37YITeUtDqWPPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}