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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '144a4c8498e30d932f7e12d188f9bc141009d1dbce4d84639f0e2a263e8b5b6a' 
  AND token = 'ih41Ym30mleuVaBFLdrvZ6rP4ojvxW2RIbYLKB8PSJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}