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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0b72c874e74d3ac8c2cc3d28eac353bf860afe686001fcc52e2e882711962bd0' 
  AND token = 'gkXjtum4GPM691L6alR6axv4a4503RvelXkWAn3pBdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}