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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4a3b1b14008c03bcedca37ef3b3c3f51af3ae864a9c868cdc1323395b846d74e' 
  AND token = 'RUE2PffRwk0nR44pdxGo3tXfkMGRu/STm70eMjuaExc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}