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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8bb50d03c0c24296a4ed694530f3a38ff566a9db1d8ead0f8a9679b4879e50e6' 
  AND token = 'XcoUUOdqiBnEWZxtaXyInlEQA6OXrE1WO1yAKcbsRyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}