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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8c3e80aefbca965e58d703e963d8569930bca02924b18fdfb099619822868666' 
  AND token = 'iKFiTm8gvii413NQSnj2RsS6RxjO7APJ2VQxEe7wWmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}