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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c8a7e4bab474b0c074fa62145cbd72fd10dfad24903305f77e0badfaf9a3e7a2' 
  AND token = '8+ISQHRyr6X3W+I3x8E4cIQjccpLJP/TI5nlshQ5sPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}