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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '07e0374314008b763f2cad9799f3890ef9878c21fa91aa4a363494ab9ab68fc5' 
  AND token = 'dZxtKAY6Tsh2+vVmErrFeOgl6hkoPLLbEcAxlhLL1jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}