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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cb6ec0283b1f8427cb8a5f73d77f92cdf5890979e5549e1a6c211f487354c960' 
  AND token = 'ZUT4dki50DVqOllWFs/wdINAhjQ6fpnNuEcIlkOnnEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}